Addison's disease Symptoms and Causes - Ahmedabad

Addison's disease symptoms and causes are often difficult to detect in the early stages, as the condition develops gradually. Addison’s disease, also known as primary adrenal insufficiency, occurs when the adrenal glands fail to produce enough cortisol and aldosterone—hormones that are critical for managing metabolism, blood pressure, and the body's response to stress.

What Causes Addison’s Disease?

The most common cause is autoimmune damage, where the immune system mistakenly attacks the adrenal glands. Other potential causes include:

• Infections such as tuberculosis

• Adrenal gland tumors or hemorrhage

• Genetic predispositions

• Side effects from long-term medication use

Key Symptoms to Look Out For

Some of the most common signs include:

• Persistent fatigue and muscle weakness

• Loss of appetite and unintentional weight loss

• Nausea, vomiting, or abdominal pain

• Craving for salty foods

• Low blood pressure and dizziness

• Hyperpigmentation of the skin, particularly in scars and folds

If left untreated, the condition may escalate into an adrenal crisis, which is a life-threatening emergency.